AKT1 and Insulin resistance: These activities are mediated by attenuation of oxidative stress, inhibition of inflammatory cascades such as nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), modulation of apoptotic pathways, and reported activation of metabolic regulators such as AMP-activated protein kinase (AMPK) and PI3K/Akt, contributing to improved glucose homeostasis and reduced insulin resistance [42,43].