The specific signaling pathways involved vary by cancer type, including JAK2/STAT3 [49,52,62], TLR4/MyD88 [61], miR-195-5p/FGFR1 [81], PADI3-ERK [59], ERK/GSK3β [76], AKT/mTOR [55], and the Toll-Like Receptor 4-Mediated Nuclear Factor-κB Signaling Pathways [50]. This evidence concerns the gene TLR4 and cancer.