In contrast, prospective device screening with implantable loop recorders (ILRs) suggests that natriuretic peptides and troponin T have their strongest association with longer subclinical AF episodes; in the LOOP program, baseline NT-proBNP and troponin T independently predicted AF detection and improved prediction of episodes ≥ 24 h when added to age/sex/comorbidity models, implying that stretch/injury signals track higher AF burden rather than short, intermittent runs [68]. Here, NPPB is linked to atrial fibrillation.