Notably, other commonly measured cardiac biomarkers—including N-terminal pro–B-type natriuretic peptide (NT-proBNP), high-sensitivity troponin T, and D-dimer—did not demonstrate predictive value in the same analysis, highlighting a divergence between subclinical device-detected arrhythmias and overt clinical AF where these markers typically perform well [64]. The gene discussed is NPPB; the disease is cardiac arrhythmia.