CXCL8 and contact dermatitis: Dermal fibroblasts participate in contact dermatitis by sensing irritants and allergens through TLRs and other receptors, subsequently producing inflammatory mediators (IL-1, IL-6, IL-8, TNF-α, CCL2, CCL5, CXCL1, CXCL8) that recruit and activate T cells and innate immune cells [168,169].