Table 1 lists the baseline characteristics of the included participants, grouped by the diagnosis of hyperbilirubinemia. The median [Q1, Q3] age of the included participants was 41 [31, 52] years; 4382 (51.77%) participants were male, 4383 (51.78%) had hyperlipidemia, and 2672 (31.57%) had hyperbilirubinemia. In general, sex, BMI, alcohol consumption, smoke status, hypertension, and levels of TC, LDL-C, HDL-C, ApoA1, ApoB, ALT, aspartate aminotransferase (AST), GGT, sCr, and UA demonstrated significant differences between the hyperbilirubinemia and nonhyperbilirubinemia groups (all p < 0.05). The gene discussed is APOB; the disease is Hyperbilirubinemia.