ADIPOQ and obesity due to melanocortin 4 receptor deficiency: This investigation evaluated the relationship between nine ADIPOQ variants rs16861194, rs17300539, rs266729, rs822395, rs822396, rs2241766, rs1501299, rs2241767, rs3774261, and PCOS–obesity risk in a cohort of Tunisian women, with allele and genotype distributions presented in Table 3.