SPN and melanoma: Although the expression of the maturation markers CD43 and CD11b was decreased in the melanoma group (p < 0.01, and p < 0.05, respectively) compared to CTRL, the percentage of NK cells expressing these markers was increased for the ALD group compared to the MbM group, significant just for CD43 (p < 0.001), with values close to the CTRL group (Figure 4b,c).