<i>Results:</i> Poor sleep quality (PSQI > 5) was associated with higher SYNTAX scores (<i>p</i> < 0.001), lower ejection fraction (<i>p</i> < 0.001), higher CRP (median 5.1 vs. 4.05, <i>p</i> = 0.029), NT-proBNP (median 748.5 vs. 595, <i>p</i> = 0.034), lower glomerular filtration rate (<i>p</i> = 0.025), and higher hypertension prevalence (<i>p</i> = 0.034). This evidence concerns the gene NPPB and Hypertension.