Therefore, the primary aim of this study was to evaluate perirenal adipose tissue thickness (PrATT) and epicardial adipose tissue thickness (EATT) in children and adolescents with T1DM compared with healthy controls, and to examine their relationships with insulin sensitivity (estimated glucose disposal rate, eGDR), cIMT, and composite cardiometabolic indices. This evidence concerns the gene INS and type 1 diabetes mellitus.