CRP and Sepsis: Furthermore, children with Influenza B demonstrated higher levels of CRP and procalcitonin and were more likely to develop sepsis, indicating a stronger systemic inflammatory response compared with Influenza A. This finding aligns with prior reports showing that Influenza B elicits greater cytokine activation and is more frequently associated with bacterial co-infection and sepsis, which may contribute to its elevated inflammatory biomarker profile [8,16].