Simultaneously, the abundance of several genera in the microbiota of cocoa-consuming animals, including Akkermansia, Roseburia, or Lactobacillus, was negatively correlated to the generation of autoAbs (anti-TG2 IgA, and anti-gliadin IgA and IgG, respectively) indicating a protective effect exerted by specific cocoa-derived taxa on one of the most clinically relevant biomarkers of CeD. This evidence concerns the gene CD79A and cranioectodermal dysplasia.