Shiga toxin-producing E. coli was found to harbor different genes such as eae, aaiC, aggR, stx2a, stx1, and stx2; however, eae, stx1 and stx2 and stx2a genes were found to be involved in a wide spectrum of gastrointestinal disorders ranging from non-bloody diarrhea to hemolytic uremic syndrome. Here, STX2 is linked to digestive system disorder.