Compared with the control group, plasma glutathione peroxidase (GSH-Px) activity (p < 0.01) and plasma superoxide dismutase (SOD) activity (p < 0.01) were notably decreased in the HF group, while plasma 8-hydroxy-2’-deoxyguanosine (8-OHdG) was markedly increased (p < 0.01). This evidence concerns the gene SOD1 and hydrops fetalis.