FDX1 and thymus atrophy: To further clarify the causal link between steroid hormone changes following ADX and thymic atrophy in female mice, we screened the aforementioned hub genes for potential glucocorticoid response elements (GRE) and estrogen response elements (ERE) in their promoter regions, spanning 1500 bp upstream and 500 bp downstream of the transcription start site using Ciiider [26].