Since previous GWAS identified variants at the IFNAR2 locus as risk factors for COVID-19 severity [8,10,14,19], to rule out that the association of IFNAR2 p.F8S variant with severe COVID-19 was due to linkage with risk alleles within the 21q22.11 locus, we performed a linkage disequilibrium (LD) analysis in the FOGS cohort among the polymorphisms in the IFNAR2 gene associated with COVID-19 susceptibility (Figure 2C,D). This evidence concerns the gene IFNAR2 and COVID-19.