MTAP and melanoma: They found that the MTAP variant rs10757257 was significantly associated with overall melanoma risk (OR = 1.32, 95% CI = 1.14–1.53), specifically for superficial spreading and nodular melanoma subtypes (OR = 1.34), but not for lentigo maligna melanoma (p for homogeneity = 0.06), which is typically linked to chronic sun exposure.