CSF1 and neoplasm: In contrast, CD155 showed a broader association pattern that included growth-factor and myeloid/stromal mediators, such as PDGF-bb, M-CSF, and TRAIL and, at the pathway level, preferential enrichment of proliferative programs (MYC/E2F/G2M), suggesting that CD155 abundance in bulk tissue may more strongly reflect tumor/stromal remodeling and tumor cell–intrinsic programs than immune activation alone.