In addition to these in silico findings, the authors assessed TIGIT expression by RT-qPCR in a cohort of 72 CRC tumors, comprising 12 MSI-H, 13 MSI-L and 47 MSS cases, and demonstrated significantly higher TIGIT expression in MSI-H tumors than in both MSI-L and MSS groups [61]. The gene discussed is TIGIT; the disease is colorectal carcinoma.