In the fully combined model incorporating DNI, CRP, and NT-proBNP (Model 5), all three biomarkers remained significantly associated with DCM, with odds ratios of 20.0 (95% CI, 8.0–50.0; p < 0.001) for DNI, 1.07 (95% CI, 1.03–1.12; p < 0.001) for CRP, and 1.30 per 1000 pg/mL (95% CI, 1.12–1.52; p < 0.001) for NT-proBNP. The gene discussed is NPPB; the disease is familial dilated cardiomyopathy.