HOTAIR and Miyoshi myopathy: Elevated HOTAIR levels are also observed in MM patients with bisphosphonate-induced osteonecrosis of the jaw (BRONJ), linking HOTAIR to bone pathology [172] (see Supplementary Tables S3 and S4, which detail HOTAIR’s mechanisms in NF-κB/JAK-STAT activation, glucocorticoid resistance, bone pathology, and exosomal transfer, together with key experimental and clinical correlations that reinforce its therapeutic and prognostic relevance).