SELP and type 2 diabetes mellitus: At baseline, T2D had significantly elevated E-selectin (p = 0.03) (Figure 1A), P-selectin (p < 0.0001) (Figure 1C), PAI-1 (p < 0.01) (Figure 1H) and angiopoietin-1 (ANGPT1) (p = 0.02) (Figure 1F), and lower cadherin-5 (p = 0.02) (Figure 1B) compared to healthy control subjects.