ROCK1 and plasma cell myeloma: A 2020 study aimed to identify genes overexpressed in myeloma stem cells that could serve as predictors for risk stratification in newly diagnosed MM patients using Ingenuity Pathway Analysis (IPA), highlighted GSK3B, along with ROCK1, also identified in our analysis, as key components of the MMSP5 gene model, both demonstrating stronger prognostic power than standard clinical parameters [25].