LIMA1 functions, at least in part, through interaction with MYO5B within tumor cells, thereby activating downstream signaling that suppresses the expression of metastasis-associated proteins (MMP9, Snail, TGF-β1) and the pro-inflammatory cytokine IL-6, while increasing the apoptosis marker cleaved caspase-3. This evidence concerns the gene CASP3 and neoplasm.