In particular, the “common EBL-related cluster” was associated with KEGG pathways directly involved in tumorigenesis, such as “MicroRNAs in cancer,” “Pathways in cancer,” “prostate cancer,” “Central carbon metabolism in cancer,” “Colorectal cancer,” “Breast cancer,” “Proteoglycans in cancer,” and “PD-L1 expression and PD-1 checkpoint pathway in cancer.” However, the pathways that are critical for the development of lymphoma remain unknown. The gene discussed is CD274; the disease is breast cancer.