Furthermore, 14 cancer-related genes were identified (CREBBP, KRAS, HDAC4, IRS2, MTOR, NOTCH1, PTEN, PDGFRB, RPTOR, TP53, ERBB4, MSH2, MSH3, and MYD88) among these 23 genes (Table 9, shown in red). The gene discussed is RPTOR; the disease is cancer.