This study is crucial because it transfers the anti-inflammatory effect, already observed in contexts of physiological stress (Gonzalez et al., 2024) and chronic diseases to an acute infectious disease, suggesting that ASX’s ability to inhibit pathways like NF-κB can be a valuable support to standard therapies for controlling the “cytokine storm” that characterizes many severe infections [141]. The gene discussed is NFKB1; the disease is infectious disease.