When stratified by adipose depot, PYCARD expression in VAT showed a non-significant trend toward reduced levels in women with PCOS (number of biopsies = 8) compared to non-PCOS controls (number of biopsies = 8) (median [IQR], 0.2384 [0.02886–1.906] vs. 1.544 [1.210–2.205], p = 0.066, respectively). Here, PYCARD is linked to polycystic ovary syndrome.