When stratified by adipose depot, CASP-1 expression remained elevated in the non-PCOS group compared to the PCOS group in both VAT (number of biopsies = 7 vs. number of biopsies = 8; mean ± SD, 1.533 ± 0.4882 vs. 0.7139 ± 0.7738, p = 0.029, respectively) and SAT (number of biopsies = 4 vs. number of biopsies = 7; 1.222 ± 0.1883 vs. 0.5198 ± 0.5609, p = 0.017, respectively). The gene discussed is CASP1; the disease is polycystic ovary syndrome.