As shown in Figure 9A, mice with MetS showed an upregulation in the gene expression of the proinflammatory cytokines TNF-α (p < 0.05), IL-1β (p < 0.01), IL-6 (p < 0.05), and MCP-1 (p < 0.05) in the aorta. This evidence concerns the gene IL6 and metabolic syndrome.