The authors analyzed the most significant genes in the RSF model and found that the mRNA expression levels of CHI3L1, FKBP9, HOXD11, IMPDH1, MDK, MYBL2, SETD8, TMEM2, and UST were significantly increased in GBM, while the expression levels of EPM2A and FLRT1 were significantly decreased in GBM. The gene discussed is EPM2A; the disease is glioblastoma.