The authors of paper [34] developed a prognostic risk score model for glioma patients based on RNA-sequencing data that incorporates 11 genes related to the cell cycle and immune response: PLOD1, CCR5, CTSZ, ITGB2, TLR2, ASPM, GINS4, KIF14, KIF2C, KPNA2, and POLD3. Here, CTSZ is linked to central nervous system cancer.