PUF60 and cancer: Regarding the association between FIR/PUF60 and cancer, there are several reports concerning various types of cancer, including lung cancer [57,58], breast cancer [59,60,61,62], ovarian cancer [63], esophageal cancer [64], gastric cancer [44,65,66,67,68], colorectal cancer [1,10,69], hepatocellular carcinoma [29,30], renal cancer [70], bladder cancer [71], and brain tumors (glioma) [72] (Figure 5).