Consistent with these observations, i.v. infusion of GIP(3–30)NH2 at 1200 pmol/kg/min during MMTs in type 2 diabetes patients significantly attenuated the normal postprandial CTX suppression without affecting P1NP [67], confirming that the anti-resorptive effects of endogenous GIP are preserved even under diabetic conditions. The gene discussed is GIP; the disease is type 2 diabetes mellitus.