In another study on the tumor microenvironment, Alexander T H Wu et al. [69] demonstrated that Ovatodiolide, isolated from Anisomeles indica, inhibits bladder carcinogenesis by suppressing mTOR/β-catenin/CDK6 signaling and exosome-mediated oncomiR released from M2 tumor-associated macrophages. The gene discussed is CDK6; the disease is neoplasm.