FAK is often over-expressed and hyper-active in various types of cancer, such as exocrine pancreas [62,63], non-small-cell lung [64], small-cell lung [65], ovarian [66], gastric [67], colorectal [68], head and neck squamous cell [69], breast [70,71], thyroid [72,73,74], hepatocellular carcinoma [75], clear-cell renal cell carcinoma [76], glioblastoma [77,78], and melanoma [79,80]. The gene discussed is PTK2; the disease is cancer.