TP53 and cancer: We found that the mRNA expression patterns of ZRANB3 and TP53 are moderately correlated across cancers overall, but that this correlation is substantially reduced when TP53 is mutated (rhoZRANB3/p53wt = 0.39; rhoZRANB3/p53mut = 0.18) (Figure 3A and Supplementary Table S3).