CXCR4 and keloid: Further research targeting this signaling pathway found that thymic stromal lymphopoietin (TSLP) in keloids acts not only as a potential initiator of collagen synthesis but also activates the CXCR4/CXCL12 axis, promoting the chemotaxis and local accumulation of fibrocytes, thereby exacerbating the pathological progression of keloid formation.