Similar patterns have been described in other leukemias, where uncommon combinations of structural lesions, for example, t(6;9)(DEK::NUP214) concurrent with inv(16)(CBFB::MYH11) in chronic myeloid leukemia, have been linked to particularly unfavorable disease progression [17]. This evidence concerns the gene CBFB and chronic myelogenous leukemia, BCR-ABL1 positive.