Clinically, CDHR1 variants are associated with cone dystrophies (COD), central areolar choroidal dystrophy (CACD), cone-rod dystrophies (CORD), rod-cone dystrophies (RCD), and late-onset macular dystrophy (LOMD) [6,12,13,14,15,16]. Here, CDHR1 is linked to central areolar choroidal dystrophy.