The frequency distribution of the minor rare G allele and the common A allele of the rs3903239 polymorphism of the PRRX1 gene in the main and the control groups was distributed as follows: the frequency of the rare G allele in the main group of patients with AF was 40.7%, and the frequency of the common A allele was 59.3%. This evidence concerns the gene PRRX1 and atrial fibrillation.