In 2018, the largest multiethnic study of the association of the genome with the left atrium in more than 500,000 participants, which included 84.2% European, 12.5% Japanese, 2% African American, and 1.3% Brazilian and Hispanic populations, confirmed the role of the PRRX1 gene in the occurrence of AF [9]. The gene discussed is PRRX1; the disease is atrial fibrillation.