Many other genes involved in cryptorchidism, hypospadias, testicular cancer, or reduced AGD, like ATF3 [134], DHH [135], DMRT1 [136], EPHX1 [137], GATA4 [138], KIT [139,140], PIWIL1 [141], SOX9 [142,143], WNT [144], and WT1 [145,146], were associated with a lower level of evidence with various degrees of semen alterations and male fertility problems. The gene discussed is WT1; the disease is hypospadias.