In all experimental models, phthalates exposure, particularly di-2-ethylhexyl phthalate/dibutyl phthalate (DEHP/DBP), can reduce testosterone and INSL3 levels as well as AGD, and is associated with an elevated risk of cryptorchidism, with the risk being higher for mixtures of compounds [12]. This evidence concerns the gene INSL3 and cryptorchidism.