CRP and irritable bowel syndrome: Gürbüzer et al. [23] conducted a prospective case–control study of 76 men with MUD and 70 matched controls, reporting significantly higher levels of NLR (2.24 ± 1.07 vs. 1.64 ± 0.43; p = 0.001), PLR (127.97 ± 39.10 vs. 108.62 ± 31.64; p = 0.004), MLR (0.29 ± 0.12 vs. 0.24 ± 0.07; p = 0.009), IBS (630.22 ± 301.53 vs. 423.12 ± 135.56; p < 0.001), CRP (7.21 ± 9.62 vs. 1.28 ± 1.19; p < 0.001), and MHR (0.02 ± 0.01 vs. 0.01 ± 0.004; p < 0.001) in the MUD group versus the control group.