The targeting relationship between miR-624-5p and FAP was validated using FISH, dual-luciferase assay, and Western blotting.<h4>Results</h4><sup>68</sup>Ga-FAPI-04 uptake was higher in advanced NSCLC (<i>p</i> < 0.001) and correlated with tumor size, lymph node metastases, and distant metastases (<i>p</i> < 0.05). Here, FAP is linked to neoplasm.