In multivariate analysis, histologic type was the only independent predictor of both MMR deficiency (adjusted OR = 15.22; 95% CI 4.99-46.37; <i>p</i> < 0.001) and p53 abnormality (adjusted OR = 79.42; 95% CI 10.60-595.05; <i>p</i> = 0.003). Here, TP53 is linked to mismatch repair cancer syndrome 1.