<h4>Background</h4>Galectin-10 (Gal-10), the main constituent of Charcot-Leyden crystals, is a recognized marker of eosinophilic inflammation, yet its role in nasal mucosal remodeling in Seasonal Allergic Rhinitis (SAR) remains poorly defined.<h4>Methods</h4>Gal-10, IL-5, MUC5AC, and IFN-γ were analyzed in Nasal lavage (NL) samples from children with SAR by ELISA. Here, CLC is linked to seasonal allergic rhinitis.