ZCWPW1 and psychotic disorder: Associations with APOE and MS4A for affective dysregulation, ZCWPW1, EPHA1, and BIN1 for psychosis-related symptoms, and NME8 for apathy highlight the possibility that MBI domains represent clinically observable phenotypes of underlying genetic susceptibilities [9,51,70,74,141,142,143,144].