NTRK1 and cervical squamous intraepithelial neoplasia: Analysis of genomic data of GC tissues indicating four molecular subtypes: EBV, MSI, GS, and CIN which each one has shown different features like extreme DNA hypermethylation for EBV, high mutation rates for MSI, low fewer genomic alterations for GS and marked aneuploidy also receptor tyrosine kinase amplifications in CIN subtype, which this may guide the personalized treatment potential regarding these features impacted on the therapeutic strategies [40].