PIK3CA and cervical cancer: A landmark multi-omic analysis by The Cancer Genome Atlas (TCGA) provided a comprehensive molecular characterization of cervical cancer, identifying APOBEC-driven mutagenesis as a dominant process and recurrent alterations in PIK3CA, PTEN, KRAS, ERBB3, CASP8, HLA-A, SHKBP1, and TGFBR2.