KDR and ovarian carcinoma: A previous study examined the growth-inhibitory characteristics of itraconazole through the implication of ovarian epithelial cancer (EOC) cell lines (SKOV3ip1) and vascular endothelial cell lines (HUVEC and SVEC4-10), and investigated angiogenic factor (VEGFR2, p-ERK, p-PLCr1/2), hedgehog (Gli1, Ptch1, SMO), and mTOR (pS6K1) signaling pathways to clarify itraconazole-related mechanistic action.