IL6 and pancreatitis: The highest diagnostic accuracy was observed in the single-timepoint study by Bhowmick et al., where an IL-6 cut-off of 46.4 pg/mL within the first 24 h predicted severe pancreatitis with a sensitivity of 96.2 percent, specificity of 95.8 percent and an AUC of 0.99 (95% CI 0.91–1.00) [29].