Infertility, reduced number of spermatozoa, abnormal morphology of spermatozoa (tail bending in a hairpin form, mitochondrial swelling, “giant-head” spermatozoa, truncated mitochondrial capsule, lack of mitochondrial capsule, fusion of midpiece and tail, and extrusion of microtubules and outerdense fibers from the tail), decreased motility, decreased sperm DNA viability, and incompletely condensed chromatin.Morphological changes in the testis and epididymis. 80% reduction of Se in the testis. The changes are the same as on the Se-deficient diet or with the ApoER2 knockout. Here, LRP8 is linked to Infertility.