Composite indices such as the C-reactive protein/albumin ratio (CAR), the CRP × fibrinogen/albumin ratio (CFA), and the modified Glasgow Prognostic Score (mGPS) integrate these parameters, although their prognostic role in T-cell acute lymphoblastic leukaemia (T-ALL) remains underexplored. The gene discussed is CRP; the disease is T-cell acute lymphoblastic leukemia.