Compared with the lowest quartile, the highest AIP quartile was associated with increased odds of overall CVD (OR = 1.73, 95% CI = 1.20–2.52, p for trend = 0.001), coronary heart disease (OR = 2.20, 95% CI = 1.20–4.25, p for trend = 0.013), and heart attack (OR = 2.53, 95% CI = 1.42–4.74, p for trend = 0.008). The gene discussed is AIP; the disease is coronary artery disorder.