NFKB1 and lymphoma: Similarly, epigallocatechin-3-gallate, the most abundant polyphenol in green tea, demonstrates dual efficacy by inhibiting the latent membrane protein 1 in EBV-co-infected lymphomas and suppressing the ROS/MAPK/NF-κB signaling axis, which is chronically activated in the HIV-infected host (Hauber et al., 2009).